The Encyclopedia of DNA Elements (ENCODE) Consortium is an ongoing international collaboration of research groups funded by the National Human Genome Research Institute (NHGRI). The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that control cells and circumstances in which a gene is active.

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参考：
An integrated encyclopedia of DNA elements in the human genome. 2012
New developments on the Encyclopedia of DNA Elements (ENCODE) data portal. 2020
Expanded Encyclopaedias of DNA Elements in the Human and Mouse Genomes. 2020

数据库架构

  • 样本

25 human (15 mouse) cell types have complete cell-type-specific cCRE classifications and 839 human (157 mouse) cell types have partial cCRE classifications.

Homo spaiens:

  1. cell line
  2. in vitro differentiated cells
  3. organoid
  4. primary cell
  5. tissue
  • 数据类型

基因组功能元件：

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数据组织：

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数据统计信息：

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  • 质控标准

参考Terms and Definitions

  • 下载

参考Rest API

生物本体数据库

Bioportal
Ontology Lookup Service
Ontobee
Cellosaurus

2022年11月30日·悼念江泽民逝世💮🕯🕯